To find the best whole house air purifiers, you'll need to examine a list of criteria to determine what is most important. We recommend the best whole house air purifier with a minimum 3-stage filtration process. This consists of a pre-filter for larger particles, a true HEPA filter for dust, spores, and allergens, and an activated carbon filter that blasts smoke, odors, and gasses to smithereens. Don't forget digital controls, such as real-time air quality reminders and Away Mode settings for energy efficiency. After analyzing hundreds of reviews, we've determined that the Alen Breathesmart Classic Large Room Whole House Air Purifier is the best whole house air purifier you can buy. Keep reading about this and our other top picks to learn more and choose the best air purifier for your home. Top 10 Best Whole House Air Purifiers #1 Alen Breathesmart Classic Large Room Whole House Air Purifier Award: TOP PICK WHY WE LIKE IT: This whole-house air purifier covers a monstrous up to 1100 square feet of living area using four HEPA type filters, an excellent choice as a No. 1 option for a large home or office. This whole house air purifier is very impressive across the board, starting with a 4-layer filtration system that uses a pre-filter, silver filter, HEPA pure filter, and an activated carbon layer that work together to cut down on allergens, dust, pollen, and other airborne contaminants as small as 0.3 microns. It uses an inner which works to release negative ions into the environment to bind to allergens, killing it on contact. We love this whole-house air purifier impressive display panel, which uses sensors to indicate filter life, air allergen sensing. An auto mode setting also allows different fan speed adjustments. Kudos for WhisperMax technology, which allows it to run very quietly without losing efficiency. Along with a 9 to 12-month filter life running 24/7, maintenance is very minimal. Compare that with the best personal air purifier that even has a filter life and maintenance information button. #2 Coway Airmega 400 Whole House Air Purifier Award: HONORABLE MENTION WHY WE LIKE IT: This whole-house air purifier clears up to 1560 square feet of living space and includes a pollution sensor, great for people who want to gauge the level of indoor air quality. This whole-house air purifier is a juggernaut, combining an activated carbon and HEPA filter hybrid with its Max2 technology to kill close to 100% of airborne contaminants, both large and as small as 0.3 microns. Its dual suction system can change the air in a room up to two times per hour with efficient airflow that directs outside of the top of the purifier. We love this whole house air purifier's suite of smart technology features, which includes auto fan speed adjustment based on pollution levels, which helps save on energy bills. It's very intuitive to use, with a four-color LED ring offering 'good', 'moderate', 'unhealthy', and 'very unhealthy' levels. A filter lifetime indicator also makes it easy to know when it is time to replace your filter. There's also a smart filter change reminder from the best air purifier and humidifier that lets users know when it is time to replace the filter. #3 Medify Air MA-112 V2.0 Whole House Air Purifier Award: BEST CIRCULATION WHY WE LIKE IT: This whole-house air purifier comes with a touch screen panel and 360° air distribution, an excellent choice for people who want equal airflow in an entire house. This whole-house air purification system is a dependable workhorse, using a pre-filter, HEPA filter activated carbon filter, and an ionizer to remove up to 99.97% of airborne contaminants. It also uses a massive Advanced Air Chamber that is capable of clearing out up to 2,400 square feet using a bottom-to-top airflow system. A 360-degree air distribution system works to direct airflow from all sides, allowing more even distribution. Big points go to a touch screen panel loaded with features, using multiple fan speeds and a set timer for further energy savings. It also includes a sleeping mode, which places it in a quiet setting, excellent for overnight use in bedrooms. Kudos for a child safety lock, which also prevents children and pets from turning it on and on accidentally. All in all, this whole house air purifier's combination of large coverage area, 4-stage filtering, and digital controls make it one of the best we've researched. For more of the coverage area, you should really compare this with the best large room air purifiers. #4 Hathaspace HSP001 Whole House Air Purifier Award: BEST FOR STUDIOS WHY WE LIKE IT: This electronic air cleaner comes with 5-in-1 filtration and replaces air twice an hour for rooms up to 350 square feet, an excellent choice for studios. This whole house air purifier leads with a 5-in-1 filtration system that consists of a cold catalyst filter, cellular activated filter, antibacterial layer, HEPA filter, and ionizer. All work to kill airborne contaminants such as dust, smoke, odors, pollen, and dust mites. With 350 square feet of coverage, this whole house air purifier is good to replace air twice an hour. On the digital side, it is very formidable, coming with an air quality sensor for real-time updates, auto more for auto fan speed adjustment, and a handheld remote control to control it within range. And for more digital purifiers, check out the best smart air purifier with an air quality sensor for real-time updates #5 Oransi Max Hepa Whole House Air Purifier Award: BEST FOR LIVING AREAS WHY WE LIKE IT: This whole house air purifier comes with three stages of filtration and works in rooms up to 600 sq ft, an excellent choice for a main living area. This whole house air purifier offers three stages of filtration, which consists of a pre-filter for larger particles, a HEPA filter for allergens, and an activated carbon filter to weave its magic with smoke and odors. One of our favorite features with this whole house air purifier is its Intelligent Air Quality Monitor, which helps monitor air quality in real-time with automatic fan speed adjustment to help save energy if needed. A filter replacement indicator also lights up an electronic display for regularly scheduled maintenance with a color-coded guide when it's time for a replacement. And another air quality indicator unit that offers real-time status updates is the best air purifier with a washable filter. #6 Germ Guardian AC4150BLCA Whole House Air Purifier Award: BEST COMPACT DESIGN WHY WE LIKE IT: This 4 in 1 desktop air purifier: comes in a compact 7.5 x 6.5 x 11-inch build and offers coverage up to up to 78 square feet, an excellent choice for smaller spaces and tabletops. This best whole house air purifier HVAC cleans 99.97% of airborne contaminants as small as 0.3 microns with a three-stage filter, which uses a pre-filter for large particles, HEPA filter for smaller particles (dust mites, pet dander), and an activated carbon filter for smoke, odors, and gases. A UV-C light also wreaks havoc on bacteria and viruses for complete protection. With room coverage of up to 78 square feet, this best whole house UV air purifier is best reserved for smaller bedrooms and offices, with ideal placement on tabletops to maximize airflow and coverage space. All in all, this compact air filter offers an excellent combination of three-stage filtration, UV-C light for germ-fighting, and a compact size for smaller spaces. Another UV light unit for germ-fighting is the best UV air purifier which has a minimum 3-stage filtration system that work to battle airborne contaminants as small as 0.3 microns. #7 IQAir Healthpro Plus Whole House Air Purifier Award: BEST FOR STUFFY NOSES WHY WE LIKE IT: This whole-house air purifier covers areas up to 1,125 sq ft with HyperHEPA filtration technology, an excellent choice for people suffering from allergies and asthma. This whole-house air purifier is very effective with clearing allergens using a HyperHEPA filtration proven to cut airborne ultrafine contaminants down by 99.5% and 0.003 microns. It uses several technologies to make this work, starting with pre max micro-particle filtration for larger particles, a V5-cell activated carbon filter for odors and smoke, and HyperHEPA filtration for ultrafine particles. Unlike most whole-house air purifiers, this one comes with a handheld remote control with six fan speeds and a filter-life monitor. We like how easy it is to replace filters with this unit. A modular tower design snaps open in two seconds using locking arm mechanisms to remove and replace filters. Fan noise is also kept at a minimum, which allows for uninterrupted sleep by children and adults. Just like the Ultra Quiet mode that automatically defaults to the lowest setting in the best plug-in air purifier. #8 Alexapure Breeze Whole House Air Purifier Award: BEST QUALITY WHY WE LIKE IT: This whole house air purifier uses IonCluster technology to release negative ions into the atmosphere, binding and killing airborne contaminants, great for people who want a well-rounded machine good for up to 800 square feet area. This whole house air purifier HVAC does an exceptional job across the board starting with a True HEPA filter capable of killing up to 99.97% of airborne particles in rooms up to 800 square feet. It uses a four-stage setup, including a pre-filter, activated carbon fiber, advanced true HEPA filter, and an ion cluster module that kills microbes. Big points go to this unit's Intelligent Auto Mode, which automatically adjusts fan speeds based on air quality in real-time. This also helps with energy efficiency, with a max 0.5KWH power usage. Color-coded lights from red to blue also indicate air quality well. Kudos for an exceptional sleep mode, only hitting 16 decibels in silent mode. One of the quietest options we’ve seen, and also recommend, is the best central air conditioner. #9 Winix 5300 Whole House Air Purifier Award: BEST FOR KITCHENS WHY WE LIKE IT: This whole house air purifier features a 4-stage filtration system and PlasmaWave to help cut down on odors, an excellent choice for people who want to eliminate messy kitchen smells. Air purification is very thorough with this unit, starting with a pre-filter for larger airborne particles, a carbon filter for odors/smoke, a HEPA filter for pollen and other ultra-fine particles, and a PlasmaWave layer to help kill bacteria and viruses. It is also very good with neutralizing odors, a must for busy kitchens. This whole house air purifier is good for up to 360 square feet of coverage. Other digital features include a Smart Sensor for real-time air quality updates and Auto Mode for optimal running. All in all, this whole house air purifier is very well rounded with a neat combination of 3-stage filtration, Smart Sensor, and a focus on eliminating bacteria and viruses. But if you're not interested in installing a permanent cooling or heating system in your home, the best portable air conditioner and heater is the perfect solution. #10 GT 3000 Whole House Air Purifier Award: BEST FOR BOATS AND RVs WHY WE LIKE IT: This whole-house air purifier covers a list-best 2,500 to 3,000 square feet of living space using GT300 technology for effective mold protection, making it an excellent choice for large homes, boats, and RVs with regular exposure to high moisture. This hospital-grade whole house air purifier uses several filtration technologies, starting with photocatalytic oxidation cell technology for the molecular breakdown of bacteria, ionization for negative ion output to battle allergens, and a combination of scalable and electrostatic filtration to cover mold and odors. The sheer number of technological features with this whole house air purifier is remarkable. Features to purify the air in your home include an Away Mode with four timer settings, a handheld remote control for light dimming. LCD screen reminders also indicate when it is time to change the filter. If you can accept its sky-high price point, it's good to go. But also remember that there are some other units that are cheaper which have LCD screen indicators, like of the best ductless mini-split air conditioners. How We Decided In determining the best whole house air purifiers to buy, we explored efficiency, versatility, and digital controls. Whole house air purifiers vary drastically in terms of square foot coverage. Look for whole house air purifiers with a minimum 3-stage filtration system that uses a pre-filter for large particles (e.g. dust mites),. true HEPA filter for smaller particles (0.3 microns), and an activated carbon filter to ease up smoke, odors, and gasses. Multiple stage filtration systems are capable of removing up to 99.97% of airborne contaminants that can exacerbate asthma symptoms, develop allergies, and illness if not treated in time. In terms of versatility, we are big fans of high-quality whole-house air handlers that clean the air well. Other technologies that could provide a boost include UV lighting to kill bacteria and germs, an ionizer to release negative ions into the atmosphere to capture airborne contaminants, and filter life indicators to note when it's time to replace your filter based on a regular schedule. We are also big fans of multiple fan speeds that allow for energy efficiency based on real-time air quality and the size of the room the unit is in. Best Whole House Air Purifiers Buyer's Guide The Most Important Features to Consider Efficiency Look for the best whole house air purifier that can eliminate up to 99.97% of airborne contaminants using a minimum 3-stage filtration system, consisting of a pre-filter, true HEPA filter, an activated carbon filter. Each is responsible for performing a wide range of functions, including trapping gasses, neutralizing odors, and charging airborne particles to kill them on contact. Square footage coverage varies wildly, anywhere from 75 square feet upwards of 3000 feet. Versatility In terms of versatility, smaller units are more capable of being allowed to mount vertically or horizontally to preserve tabletop or desktop space. Others have more neutral, minimalist tones to blend in well with home decor. Whole house air purifiers come in all shapes, sizes, and proportions. Digital Controls Full-scale digital controls are key to best manage your whole-house air purifier. We are big fans of filter life indicators, LED color-coded real-time status updates on air quality, auto fan speed adjustment, and other features designed to make it easier to manage your air quality. Don't forget a whisper-quiet operation that does not exceed 20 decibels, regardless of setting. Note, larger units are less likely to adhere to this requirement, so noise levels may be sacrificed for larger units from time to time.